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Cell Systems Biology

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Modeling & Simulation

Launched: Labscape

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Systems Support

CSI Collaborators

SigTran - Cell Signaling Simulation Software


SigTran is a modeling environment especially designed to enable biological researchers to carry out large scale simulations and analysis of complex signal transduction networks.
SigTran currently supports
  • Complete elementary reaction capability up to and including ternary reactions
  • Michaelis-Menton kinetics
  • Clamping of species copy numbers
  • Multistate specification and simulation
  • Tagged molecule or reaction tracking
  • DAE based kinetic simulations for comparison with stochastic simulations and model debugging
  • Ensemble simulation with run time and post run time statistical processing
  • Graphical display and plotting of simulation output.
SigTran is freely available for downloading and testing. Questions and comments should be directed to the Modeling Group at Cell Systems Initiative modeling@cellsystems.org.

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Department to Bioengineering University of Washington